This article reports the case of a depressive woman with paroxetine-induced sleep bruxism who was successfully treated with buspirone. It has been hypothesized that the mechanism for SSRI-induced bruxism may involve excessive serotonergic action on the meso-cortical neurons arising from the ventral tegmental area.INTRODUCTION · CASE DESCRIPTION · DISCUSSION. J Clin Psychiatry. Dec;60(12) Buspirone as an antidote to SSRI-induced bruxism in 4 cases. Bostwick JM(1), Jaffee MS. Author information: (1)Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minn , USA. BACKGROUND: One hypothesis to explain selective serotonin reuptake inhibitor.
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Despite numerous case reports, the evidence for treatment of bruxism is still low. Different treatment modalities (behavioral techniques, intraoral devices, medications, and contingent electrical stimulation) have been applied. A clinical evaluation is needed to differentiate between awake bruxism and sleep Primary bruxism · Bruxism associated with · Bruxism as an adverse · Conclusion. dopaminergic deficit which in turn causes akathisia- like movement of jaw muscles leading to bruxism. (Bostwick and Jaffee, ). Buspirone a partial agonist at 5-HT1A receptors has been found to improve bruxism caused by SSRIs and venlafaxine (Bostwick and Jaffee, ; Jaffee and Bostwick, ;.
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