Yalkowsky reports the solubility of Doxyxycline, mg/L (at 25 °C) or ug/ml (profitmaker.info), this is soluble, so I recommend using cosolvents (EtOH+W, PG+W, PLG +W) or the best ultrasound at 40 ° C. 4 years ago. Deleted profile. Added an answer. Thank you. 4 years ago. Deleted profile. Solubility of doxycycline in aqueous solution. Bogardus JB, Blackwood RK Jr. The solubility of doxycyline monohydrate and doxycycline hydrochloride dihydrate was investigated in aqueous solution. The hydrochloride dihydrate salt was isolated and identified from solutions initially containing doxycycline hyclate in water.
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doxycycline | C22H24N2O8 | CID - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, Water Solubility. mg/L (at 25 °C). YALKOWSKY,SH & DANNENFELSER,RM (). from DrugBank. VERY SLIGHTLY SOL IN WATER; SPARINGLY SOL IN. Doxycycline belongs to the group of tetracyclines and acts bacteriostatic against many Grampositive and Gram-negative bacteria like Bordetella, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. Doxycycline.
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